Evaluation of free-radical quenching properties of standard Ayurvedic formulation Vayasthapana Rasayana
2011
Antioxidant Properties of Ayurvedic Formulation Vayasthapana Rasayana
publication
Evidence: moderate
Author Information
Author(s): Sourav Mukherjee, Nayana Pawar, Omkar Kulkarni, Bhagyashri Nagarkar, Shrikant Thopte, Akshay Bhujbal, Pankaj Pawar
Primary Institution: Bharati Vidyapeeth University
Hypothesis
The study investigates the in vitro free-radical quenching capacity of the Ayurvedic formulation Vayasthapana Rasayana.
Conclusion
The study validates the potential use of Vayasthapana Rasayana as an antioxidant to combat age-related problems.
Supporting Evidence
- The formulation showed 94% DPPH free-radical scavenging activity at 0.1 mg/ml.
- The IC50 value for the formulation was 5.51 μg/ml, significantly lower than the standard ascorbic acid's 39 μg/ml.
- The total phenolic content of the formulation was 8.3 mg per g of dry mass.
- The total antioxidant capacity estimated by FRAP was 1150 ± 5 μM Fe(II)/g dry mass.
Takeaway
This study shows that a traditional herbal mix can help fight the bad stuff in our bodies that makes us age faster.
Methodology
The study used methanol extracts of the formulation and performed in vitro assays like DPPH, FRAP, and ABTS to evaluate antioxidant activity.
Digital Object Identifier (DOI)
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