Predictors of Mortality in Children Admitted to a Hospital in Uganda
Author Information
Author(s): Ochora Moses, Kyoyagala Stella, Kyasimire Lydia, Akambasisa Mercy, Twine Margaret, Ahmed Muna, Lutasingwa Dan, Nampijja Dorah, Kumbakumba Elias
Primary Institution: Department of Paediatrics and Child Health, Mbarara University of Science and Technology, Mbarara, Uganda
Hypothesis
What are the patterns and predictors of mortality within the first 24 hours of admission among children aged 1–59 months?
Conclusion
The study found a high mortality rate of 7.7% within the first 24 hours of admission, primarily due to severe pneumonia and malnutrition.
Supporting Evidence
- Most deaths occurred within the first 24 hours of admission.
- Severe pneumonia and severe acute malnutrition were the leading causes of death.
- Children admitted at night had a higher risk of mortality.
- An abnormal neutrophil count was associated with increased mortality risk.
- More than two-thirds of children died within 12 hours of admission.
Takeaway
This study looked at why some children die soon after being admitted to the hospital, finding that many deaths happen quickly and are often due to treatable problems.
Methodology
A prospective cohort study was conducted among 208 children aged 1–59 months admitted to a regional hospital.
Limitations
The study was limited to a single setting and had restricted laboratory investigations due to resource constraints.
Participant Demographics
Children aged 1–59 months, with a median age of 13.0 months.
Statistical Information
P-Value
0.047 for night admissions, 0.034 for abnormal neutrophil count
Confidence Interval
95% CI 4–12 for mortality rate, 95% CI 1.02–13.53 for night admissions, 95% CI 1.10–11.31 for abnormal neutrophil count
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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