Lifestyles, environmental and phenotypic factors associated with lip cancer: a case–control study in southern Spain
2003

Factors Linked to Lip Cancer in Southern Spain

Sample size: 344 publication 10 minutes Evidence: moderate

Author Information

Author(s): Perea-Milla López E, Miñarro-del Moral R M, Martínez-García C, Zanetti R, Rosso S, Serrano S, Aneiros J F, Jimenez-Puente A, Redondo M

Primary Institution: Unidad de investigación, Hospital Costa del Sol, Marbella, Spain

Hypothesis

This study aims to determine the association between male lip cancer and tobacco consumption, alcohol intake, and various environmental and socioeconomic factors.

Conclusion

The study found significant associations between lip cancer and tobacco and alcohol consumption, as well as cumulative sun exposure.

Supporting Evidence

  • Smoking was found to be a significant risk factor for lip cancer.
  • Alcohol consumption was more frequently reported by the case group than by the controls.
  • Lifetime cumulative sun exposure was associated with an increased risk of lip cancer.

Takeaway

This study shows that smoking, drinking alcohol, and being in the sun a lot can increase the risk of getting lip cancer.

Methodology

A population-based case–control study was conducted with 105 cases of lip cancer and 239 controls, using interviews and a standardized questionnaire to gather data on tobacco and alcohol consumption, sun exposure, and demographic factors.

Potential Biases

The study may have underreported cases due to outpatient treatment and misclassification of cancer types.

Limitations

Potential biases include misclassification of lip-skin neoplasms and socioeconomic factors affecting participant selection.

Participant Demographics

Males aged 20–70 years from Granada, Spain.

Statistical Information

P-Value

p<0.05

Confidence Interval

95% CI: 3.3–37.5

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1038/sj.bjc.6600975

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