Intracranial Ependymoma: Clinical Features and Treatment Outcomes
Author Information
Author(s): Badary Amr, Kurdi Sarah Zuhair, Almealawy Yasser F., Alrubaye Sura N., Sanker Vivek, Chaurasia Bipin, Atallah Oday
Primary Institution: Department of Neurosurgery, University of Kufa, Iraq
Hypothesis
What are the clinical features, treatment modalities, and long-term outcomes of patients with intracranial ependymomas?
Conclusion
Complete tumor resection and postoperative radiotherapy are crucial for improved outcomes in ependymomas.
Supporting Evidence
- Complete resection was achieved in 87.0% of cases.
- Postoperative radiotherapy was given to 91.0% of grade 2 and all grade 3 tumors.
- Recurrence occurred in 17.4% of grade 2 ependymomas, but none of grade 3.
Takeaway
This study looked at patients with a type of brain tumor called ependymoma and found that removing the tumor completely and giving radiation afterward helps patients do better.
Methodology
A retrospective review of 23 patients with intracranial ependymomas, treated from 2018 to 2023, was conducted, assessing demographics, clinical presentations, KPSS scores, imaging findings, and treatment details.
Potential Biases
The small sample size poses a high risk of bias.
Limitations
The small sample size may limit the statistical power and generalizability of the findings.
Participant Demographics
The cohort was predominantly male (87.0%), with a mean age of 27 years.
Statistical Information
P-Value
p<0.05
Confidence Interval
95% CI: 0.982–1.124
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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