Wound Healing Activity of Colutea cilicica Extracts
Author Information
Author(s): Ipek Peşin Süntar, Koca Ufuk, Esra Küpeli Akkol, Yılmazer Demet, Alper Murat
Primary Institution: Gazi University
Hypothesis
The study aims to investigate the wound healing activity of aqueous extracts from Colutea cilicica.
Conclusion
The aqueous extract of Colutea cilicica fruits showed significant wound healing activity, comparable to the reference drug Madecassol.
Supporting Evidence
- The fruit extract showed a 78.1% contraction in wounds, close to the reference drug's 100%.
- The extract increased wound tensile strength by 42% compared to flowering aerial parts.
- Histopathological examination supported the wound healing results.
- Zinc and vitamin C levels in the extracts may contribute to the healing process.
Takeaway
This study found that a plant called Colutea cilicica can help heal wounds, just like some medicines.
Methodology
The study used incision and excision wound models on rats and mice to assess the wound healing activity of the plant extracts.
Limitations
The study did not analyze the long-term effects of the extracts on wound healing.
Participant Demographics
Male Sprague-Dawley rats and Swiss albino mice were used in the study.
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website