Quantifying behavioural interactions between humans and mosquitoes: Evaluating the protective efficacy of insecticidal nets against malaria transmission in rural Tanzania
2006

Effectiveness of Insecticide-Treated Nets Against Malaria in Tanzania

Sample size: 398 publication 10 minutes Evidence: high

Author Information

Author(s): Killeen Gerry F, Kihonda Japhet, Lyimo Edith, Oketch Fred R, Kotas Maya E, Mathenge Evan, Schellenberg Joanna A, Lengeler Christian, Smith Thomas A, Drakeley Chris J

Primary Institution: Ifakara Health Research and Development Centre

Hypothesis

Does increased coverage of insecticide-treated nets (ITNs) affect mosquito biting behavior and malaria transmission?

Conclusion

ITNs remain highly effective in providing protection against malaria transmission despite potential changes in mosquito behavior.

Supporting Evidence

  • ITNs provide over 70% protection against malaria transmission for users compared to non-users.
  • Approximately 90% of mosquito bites occur indoors and during peak sleeping hours.
  • High levels of ITN coverage have not significantly reduced malaria transmission intensity for non-users.

Takeaway

Using special nets while sleeping helps keep mosquitoes away and reduces the chance of getting malaria, even if some mosquitoes change their habits.

Methodology

Surveys of mosquito biting activity were conducted before and after ITN promotion, combined with human behavioral questionnaires.

Potential Biases

Potential bias due to reliance on self-reported data from human behavioral surveys.

Limitations

The study did not sample mosquitoes during early morning hours when biting activity may peak.

Participant Demographics

Participants were from rural villages in the Kilombero Valley, Tanzania.

Statistical Information

P-Value

0.0001

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2334-6-161

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