Hospital Mortality in Acute Coronary Syndrome: Gender Differences and Procedures
Author Information
Author(s): Aguado-Romeo María J, Márquez-Calderón Soledad, Buzón-Barrera María L
Primary Institution: Andalusian Agency for Health Technology Assessment
Hypothesis
Are there differences in in-hospital mortality between men and women with acute coronary syndrome, and do these differences relate to the use of percutaneous cardiovascular procedures?
Conclusion
Women without percutaneous procedures have higher in-hospital mortality compared to men, but gender does not affect mortality in patients who undergo such procedures.
Supporting Evidence
- Mortality was 9.6% overall, with 11.8% for women and 8.3% for men.
- Older patients and those with higher co-morbidity had higher mortality rates.
- Lower mortality was associated with patients undergoing diagnostic catheterisation and/or PTCA.
Takeaway
This study found that women are more likely to die in the hospital from heart problems if they don't get certain heart procedures, but if they do get those procedures, their chances are similar to men's.
Methodology
Observational study using data from emergency hospital admissions for acute coronary syndrome across 32 hospitals over four years.
Potential Biases
Under-reporting of procedures and inability to analyze certain clinical variables may introduce bias.
Limitations
The study relies on secondary data, limiting the analysis of other potential factors influencing mortality.
Participant Demographics
The study included 46,007 cases, with 16,391 women and 29,616 men.
Statistical Information
P-Value
0.003
Confidence Interval
95% CI: 1.06–1.22
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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