Helicobacter Pylori and Antral Gastritis in Peptic Ulcer Patients
Author Information
Author(s): GH. JEELANI ROMSHOO, G.M. MALIK, M. YOUSSUF BHAT, AB. RASHID RATHER, JAVAID AHMAD BASU, KHURSHEED AHMAD QURESHI
Primary Institution: SMHS Hospital, Srinagar, Kashmir, India
Hypothesis
To study the association of Helicobacter pylori infection with chronic antral gastritis in peptic ulcer disease patients and healthy population of Kashmir.
Conclusion
There is a highly significant association between Helicobacter pylori infection and chronic antral gastritis in both peptic ulcer disease patients and healthy volunteers.
Supporting Evidence
- 90% of peptic ulcer patients with chronic antral gastritis tested positive for H. pylori.
- 87.50% of healthy volunteers with chronic antral gastritis tested positive for H. pylori.
- 76% of peptic ulcer patients were positive for H. pylori on Giemsa Staining.
- 33.33% of healthy volunteers were positive for H. pylori.
Takeaway
This study found that many people with stomach problems and even some healthy people have a germ called Helicobacter pylori that can cause stomach issues.
Methodology
50 peptic ulcer patients and 30 healthy volunteers were studied using endoscopic examination and biopsies to diagnose H. pylori infection.
Participant Demographics
42 males and 8 females in the peptic ulcer group; 25 males and 5 females in the healthy volunteer group.
Statistical Information
P-Value
p<0.005
Statistical Significance
p<0.005
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