SNPmplexViewer--toward a cost-effective traceability system
2011

SNPmplexViewer: A Cost-Effective Tool for DNA Traceability

publication Evidence: moderate

Author Information

Author(s): Yanir Seroussi, Andrey Shirak, Eyal Seroussi

Primary Institution: Monash University

Hypothesis

Can SNPmplexViewer reduce the cost of DNA-based traceability in cattle by embedding size standards in trace files?

Conclusion

SNPmplexViewer enables cost-effective genotyping of SNaPshot reactions without fluorescent size standards, improving software performance.

Supporting Evidence

  • SNPmplexViewer allows for the analysis of trace files without the need for expensive fluorescent size standards.
  • The tool improves the performance of genotyping software by providing normalized trace outputs.
  • SNPmplexViewer is available online for free, making it accessible for researchers.

Takeaway

SNPmplexViewer is a free tool that helps scientists analyze DNA traces more cheaply by using a computer program to add important information to the data.

Methodology

The tool uses a Perl script to analyze DNA trace files, normalizing and aligning data to embed size standards.

Limitations

The algorithm may not efficiently align traces from microsatellites due to their complex stutter patterns.

Digital Object Identifier (DOI)

10.1186/1756-0500-4-146

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