Effect of Platelet-Rich Fibrin Coating on Dental Implants
Author Information
Author(s): Muacevic Alexander, Adler John R, Khattri Shivi, Kaushik Mayur, Tomar Nitin, Ahmed Sameer, Rana Nazar, Khan Mehvish, Singh Soundarya, Singh Roopse
Primary Institution: Subharti Dental College, Swami Vivekanand Subharti University, Meerut, IND
Hypothesis
Does the application of platelet-rich fibrin (PRF) on delayed dental implants enhance their secondary stability?
Conclusion
The study found low certainty evidence that PRF coating may enhance the stability of dental implants.
Supporting Evidence
- 12 trials involving 456 dental implants were included in the review.
- Meta-analysis showed a mean difference in ISQ values at four weeks of 3.34.
- At six weeks, the mean difference was 2.53, indicating increased stability with PRF.
- At 12 weeks, the mean difference was 3.37, suggesting PRF may enhance stability.
Takeaway
Using a special blood product called platelet-rich fibrin on dental implants might help them stay stable better, but we aren't completely sure.
Methodology
A systematic review and meta-analysis of randomized controlled trials and controlled clinical trials assessing the effect of PRF on dental implant stability.
Potential Biases
Six studies showed a high risk of bias, while three had a low risk and three had an unclear risk.
Limitations
The certainty of evidence was low due to the presence of non-randomized studies and high risk of bias in some included studies.
Participant Demographics
The studies included systemically healthy individuals requiring dental implant placement.
Statistical Information
Confidence Interval
95% CI 2.24 to 4.43; 95% CI 0.85 to 4.20; 95% CI 0.69 to 6.06
Digital Object Identifier (DOI)
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