Correlation Between BMI and Kidney Tumor Lateralization: Insights into Survival and Risk Factors
2024

Correlation Between BMI and Kidney Tumor Lateralization

Sample size: 287 publication 10 minutes Evidence: moderate

Author Information

Author(s): Czajkowski Mateusz, Falis Michał, Żawrocki Anton, Sternau Magdalena, Lubiewski Andrzej, Rytlewska Magdalena, Matuszewski Marcin

Primary Institution: Medical University of Gdańsk

Hypothesis

What is the relationship between body mass index (BMI) and the lateralization of kidney tumors in patients undergoing surgery for renal cell carcinoma?

Conclusion

Right-sided kidney tumors occurred significantly more frequently in overweight individuals, but there was no correlation between tumor lateralization and overall or cancer-specific survival.

Supporting Evidence

  • Right-sided kidney tumors occurred more frequently than left-sided ones.
  • A statistically significant relationship was observed between BMI and the frequency of right-sided kidney tumors in the overweight group.
  • The 5-year survival rate was 62% with a mean follow-up duration of 104 months.
  • No statistically significant difference was observed between right- and left-sided cancer groups in terms of survival rates.

Takeaway

The study found that people who are overweight are more likely to have kidney tumors on the right side, but this doesn't affect how long they live after treatment.

Methodology

This single-center study included 287 patients who underwent surgical treatment for kidney tumors and analyzed their BMI and tumor lateralization.

Potential Biases

The study may have bias due to the limited number of participants and the retrospective collection of data.

Limitations

The study is limited by its single-center design and retrospective nature, which may affect the generalizability of the findings.

Participant Demographics

The median age of participants was 64 years, with a range from 28 to 88 years; 64.46% were male.

Statistical Information

P-Value

0.04731

Statistical Significance

p = 0.04731

Digital Object Identifier (DOI)

10.3390/cancers16244139

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