Standardizing Metrics for Stroke Recovery
Author Information
Author(s): Akkara Yash, Afreen Ryan, Lemonick Michael, Paz Santiago Gomez, Rifi Ziad, Tosto Jenna, Putrino David, Mocco J., Bederson Joshua, Dangayach Neha, Kellner Christopher P., Lattanzi Simona
Primary Institution: Imperial College London; Icahn School of Medicine at Mount Sinai; Mount Sinai Health System
Hypothesis
Can a standardized set of metrics for stroke rehabilitation be identified from the literature?
Conclusion
The study identified a comprehensive set of domains and metrics for measuring stroke recovery, which can enhance clinical research and decision-making.
Supporting Evidence
- 324 studies were included in the final analysis, covering a sample of 85,156 participants.
- Seven domains of stroke recovery were identified, including physical function and quality of life.
- Eighteen standard metrics were identified to measure all domains and subdomains of stroke recovery.
- Physical and motor function was the most commonly tested domain, while quality of life was less represented.
- Statistical analysis showed significant trends in the representation of recovery domains over time.
Takeaway
This study looked at how to measure recovery after a stroke and found a list of important areas to focus on, helping doctors understand how to help patients better.
Methodology
A systematic review was conducted using PRISMA guidelines on stroke recovery articles from 2004 to 2024, including studies with at least 20 participants and a follow-up of at least 3 months.
Potential Biases
Potential bias due to the predominance of studies from high-income countries and underrepresentation of women and elderly populations.
Limitations
The study may not fully represent global stroke populations due to skewed demographics and exclusion of studies with shorter follow-up periods.
Participant Demographics
Mean age of participants was 64.51 years, with 57.7% male and 43.2% female.
Statistical Information
P-Value
p<0.0001
Confidence Interval
[0.004079, 0.7422]
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
Want to read the original?
Access the complete publication on the publisher's website