Infection Rates in Hip and Knee Surgery for Osteoarthritis
Author Information
Author(s): Gresch Maximilian, von Dercks Nikolaus, Dietze-Jergus Nadine, Roth Andreas, Pempe Christina
Primary Institution: University Hospital Leipzig
Hypothesis
Are infection rates higher in patients with post-traumatic osteoarthritis compared to those with primary osteoarthritis after total hip and knee arthroplasty?
Conclusion
Patients with post-traumatic osteoarthritis are more likely to develop periprosthetic joint infections than those with primary osteoarthritis.
Supporting Evidence
- Patients with post-traumatic osteoarthritis had a higher incidence of periprosthetic joint infections after surgery.
- Staphylococcus spp. was the most frequently detected pathogen in both types of surgeries.
- More pathogens were susceptible to vancomycin than to cefuroxime or clindamycin.
Takeaway
This study found that people who had surgery for joint problems after an injury are more likely to get infections than those who had surgery for regular wear and tear.
Methodology
A retrospective analysis of clinic-owned data from patients who underwent total hip or knee arthroplasty between January 2016 and December 2020.
Potential Biases
Potential bias due to the retrospective nature of the study and the exclusion of patients without infections.
Limitations
The study is limited by its retrospective design, small sample size, and the fact that it only analyzed patients with known or suspected infections.
Participant Demographics
The mean age of patients with infections was 65 years, with 41.3% being female.
Statistical Information
P-Value
p = 0.003 for THA, p = 0.028 for TKA
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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