Tumour necrosis factor: a cytokine with multiple biological activities
1990
Tumour Necrosis Factor: A Cytokine with Multiple Biological Activities
publication
Author Information
Author(s): G. Semenzato
Primary Institution: Istituto di Medicina Clinica dell' Universita' di Padova
Conclusion
Tumour necrosis factor (TNF) plays a crucial role in various biological processes, including immunity, inflammation, and cancer cell modulation.
Supporting Evidence
- TNF can induce necrosis in tumors and has been shown to have both cytotoxic and cytostatic effects on various cell lines.
- TNF plays a key role in the inflammatory response by stimulating endothelial cells and recruiting immune cells.
- High levels of TNF have been associated with poor prognosis in various diseases, including cancer.
Takeaway
TNF is a special protein that helps our body fight infections and can also affect how cancer cells grow.
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