Clinical Characteristics and Outcomes of Elderly Patients Undergoing Primary Percutaneous Coronary Intervention: An Observational Cohort Study
2024

Outcomes of Elderly Patients Undergoing Primary PCI

Sample size: 3627 publication Evidence: moderate

Author Information

Author(s): Hassan Ahmed, Emam Amr Yosry, Thabet Mohammed, Osman Ahmed, Shams Khaled Ahmed, Labib Mina Samir, Elguindy Ahmed

Primary Institution: Cairo University, Egypt

Hypothesis

What are the clinical characteristics and in-hospital outcomes of elderly patients undergoing primary percutaneous coronary intervention (pPCI) for STEMI?

Conclusion

Elderly patients undergoing pPCI have higher rates of complications and in-hospital mortality compared to younger patients.

Supporting Evidence

  • Elderly patients had a higher prevalence of hypertension (57.7% vs. 40.9%) and chronic kidney disease (37.6% vs. 8.2%) compared to younger patients.
  • In-hospital mortality was significantly higher in the elderly group (14.1% vs. 4%).
  • Octogenarians had an even higher mortality rate of 23.3%.
  • Killip class ≥II was an independent predictor of increased hospital mortality across all age groups.

Takeaway

Older people who have heart attacks and get a special procedure called pPCI are more likely to have problems and die in the hospital than younger people.

Methodology

This observational cohort study analyzed data from a pPCI registry at a tertiary cardiac center in upper Egypt, including 3,627 patients from January 2014 to June 2023.

Potential Biases

The study may not represent all elderly patients as it only includes those who underwent pPCI at a specific center.

Limitations

The study is based on a single center's data and lacks long-term follow-up.

Participant Demographics

The elderly group (≥70 years) included 575 patients, with a higher proportion of women and comorbidities like hypertension and chronic kidney disease.

Statistical Information

P-Value

<0.001

Statistical Significance

p<0.001

Digital Object Identifier (DOI)

10.5334/gh.1383

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication