The role of PPAR in fungal keratitis
2024
The Role of PPAR in Fungal Keratitis
publication
10 minutes
Evidence: moderate
Author Information
Author(s): Zhou Hongyan, Zhang Hong, Bi Miaomiao, Zhang Wensong
Primary Institution: The China-Japan Union Hospital of Jilin University
Hypothesis
PPARs may play a significant role in the treatment of fungal keratitis.
Conclusion
PPARs have potential therapeutic effects in managing fungal keratitis by regulating inflammation and oxidative stress.
Supporting Evidence
- Fungal keratitis accounts for 40% to 50% of all cases of microbial keratitis.
- PPARs can regulate inflammation and oxidative stress, which are critical in fungal keratitis.
- PPAR agonists have shown promise in treating various inflammatory diseases.
Takeaway
Fungal keratitis is a serious eye infection, and PPARs could help treat it by reducing inflammation and protecting the eye.
Methodology
This review explores the roles of PPARs in fungal keratitis treatment based on existing literature.
Limitations
The review is based on existing studies and may not include all recent findings.
Digital Object Identifier (DOI)
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