Ethnopharmacological evaluation of radal (leaves of Lomatia hirsuta) and isolation of 2-methoxyjuglone
2006

Study of Radal Leaves and Their Antifungal Properties

publication Evidence: moderate

Author Information

Author(s): Simonsen Henrik T, Adsersen Anne, Berthelsen Louise, Christensen Søren B, Guzmán Alfonso, Mølgaard Per

Primary Institution: Royal Veterinary and Agricultural University; Danish University of Pharmaceutical Sciences

Hypothesis

The study aims to evaluate the antifungal activity of extracts from the leaves of Lomatia hirsuta, commonly known as radal.

Conclusion

The presence of phenolic acids with antimicrobial properties supports the traditional use of Radal and encourages further studies.

Supporting Evidence

  • 2-Methoxyjuglone was isolated from the leaves and found to be active against Candida albicans.
  • Cinnamic acid and vanillic acid were identified as major constituents in the tea.
  • The tea was found not to be toxic against Artemia salina.

Takeaway

Radal leaves can help fight certain fungi, and people have used them for coughs and asthma for a long time.

Methodology

The study involved screening extracts of radal leaves for antifungal and toxic activities using various methods including GC-MS.

Limitations

The study does not address potential toxicity to human cells from the tea made from radal leaves.

Digital Object Identifier (DOI)

10.1186/1472-6882-6-29

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