Optimizing search strategies to identify randomized controlled trials in MEDLINE
2006

Improving Search Strategies for Randomized Controlled Trials in MEDLINE

Sample size: 61 publication 10 minutes Evidence: high

Author Information

Author(s): Zhang Li, Ajiferuke Isola, Sampson Margaret

Primary Institution: University of Saskatchewan

Hypothesis

Can the addition of specific search terms improve the identification of randomized controlled trials in MEDLINE?

Conclusion

Adding the term 'versus' to the top two phases of the Highly Sensitive Search Strategy improves the balance of sensitivity and precision in identifying relevant studies.

Supporting Evidence

  • The study found that using 'versus' improved the identification of relevant studies slightly.
  • Using all three phases of the Highly Sensitive Search Strategy retrieved more relevant articles than using just the top two phases.
  • The median number of included studies per review was 12.
  • Overall sensitivity for the proposed search strategies was very high, with a median of 100%.

Takeaway

This study looked at how to find more relevant medical studies using better search terms, and found that using 'versus' helps a little bit.

Methodology

The study replicated subject searches for 61 Cochrane reviews and tested six search strategies to calculate sensitivity and precision.

Potential Biases

Missing relevant studies may result in bias in systematic reviews.

Limitations

The study only tested how many included studies could be retrieved, not whether missing studies would change review outcomes.

Participant Demographics

The reviews included studies from various medical fields, primarily focusing on treatment.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1186/1471-2288-6-23

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