Study of a New Compound with Biological Activity
Author Information
Author(s): Fun Hoong-Kun, Quah Ching Kheng, Kalluraya Balakrishna
Primary Institution: Universiti Sains Malaysia
Hypothesis
The introduction of a thiadiazine moiety at the 4-position of phenylsydnone will yield compounds with enhanced biological activity.
Conclusion
The compound C18H14N6O2S exists in both trans and cis configurations and forms a three-dimensional network in the crystal structure.
Supporting Evidence
- The compound was found to exist in both trans and cis configurations.
- The crystal structure shows a three-dimensional network formed by hydrogen bonds.
- Intermolecular π–π interactions were observed between the oxadiazol-3-ium rings.
Takeaway
Scientists created a new chemical compound and found that it has a special structure that helps it connect with other molecules, which might make it useful for medicine.
Methodology
The compound was synthesized through the condensation of 4-bromoacetyl-3-arylsydnones with N'-(phenylmethylidene)carbonohydrazide and analyzed using X-ray crystallography.
Digital Object Identifier (DOI)
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