Common Bile Duct Obstruction by Free Floating Tumor
1993
Common Bile Duct Obstruction by Free Floating Tumor
Sample size: 6
publication
Evidence: low
Author Information
Author(s): Richard A. Prinz, Tien C. Ko, Sheldon B. Maltz, Carlos J. Reynes, Richard E. Marsan, Robert J. Freeark
Primary Institution: Loyola University Medical Center
Hypothesis
Can tumor cells shed into the common bile duct cause obstruction?
Conclusion
Benign or malignant tumors can shed tissue into the common bile duct, leading to biliary obstruction.
Supporting Evidence
- All six patients had jaundice and upper abdominal discomfort.
- Preoperative total serum bilirubin ranged from 2.5 to 16.1 mg/dl.
- Ultrasound showed a dilated gallbladder in five patients.
- Frozen section identified tumor tissue in all patients.
- Two patients with metastatic colon cancer died within one year of operation.
Takeaway
Sometimes, pieces of tumors can float into the bile duct and block it, making people feel sick.
Methodology
The study involved six patients treated for tumor tissue fragments in the common bile duct, with various diagnostic and surgical procedures performed.
Limitations
The study is based on a small sample size of six patients.
Participant Demographics
Three men and three women, ages 41 to 88, mean age 64.
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