Bovine epizootic encephalomyelitis caused by Akabane virus in southern Japan
2008

Bovine Encephalomyelitis Caused by Akabane Virus in Japan

Sample size: 180 publication 10 minutes Evidence: moderate

Author Information

Author(s): Kono Ryota, Hirata Miki, Kaji Masaya, Goto Yukitoshi, Ikeda Shogo, Yanase Tohru, Kato Tomoko, Tanaka Shogo, Tsutsui Toshiyuki, Imada Tadao, Yamakawa Makoto

Hypothesis

The study aims to define the epidemiological, pathological, and virological properties of Akabane virus-induced encephalomyelitis in cattle.

Conclusion

A new strain of Akabane virus invaded southern Japan in 2006, causing a large-scale outbreak of encephalomyelitis primarily in calves.

Supporting Evidence

  • Nonsuppurative encephalomyelitis was observed in affected cattle.
  • Akabane viral antigen and genome were detected in the central nervous system of affected cattle.
  • The outbreak affected 180 cattle across five prefectures in southern Japan.

Takeaway

A virus called Akabane caused a lot of sick calves in Japan, making them have problems with their nerves.

Methodology

The study involved clinical observations, histopathological analysis, serological surveys, and viral isolation from affected cattle.

Limitations

The study does not provide detailed information on the long-term effects of the outbreak or the effectiveness of existing vaccines.

Participant Demographics

Cattle aged from 4 days to 96 months, primarily under 24 months old.

Digital Object Identifier (DOI)

10.1186/1746-6148-4-20

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