Sleep and Cortisol Impact Cognitive Outcomes in Midlife Hispanic/Latine Adults at Risk for Alzheimer’s Disease
Author Information
Author(s): Burke Shanna, Gonzales Samantha, Grudzien Adrienne, Cambara Celine, Briceno Alexandra, Jimenez Daniel, Scott Stephanie, Martinez Sabrina Sales
Primary Institution: Florida International University
Hypothesis
How do sleep and cortisol levels affect cognitive test outcomes in Hispanic/Latine adults at risk for Alzheimer's disease?
Conclusion
The study found that sleep efficiency and fragmentation significantly impact cognitive performance in adults at risk for Alzheimer's disease.
Supporting Evidence
- Sleep efficiency was significantly associated with executive attention.
- Sleep fragmentation was significantly associated with immediate memory.
- Cortisol at waking affected episodic memory based on sleep efficiency.
- The interaction between sleep duration and cortisol at bedtime was linked to nonverbal memory.
Takeaway
Getting good sleep is really important for our brains, especially for people who might get Alzheimer's disease.
Methodology
Cortisol was measured from saliva and cognition was assessed using the NACC Neuropsychological Battery, while sleep was measured with actigraphy.
Participant Demographics
Hispanic/Latine adults with first-degree relatives with Alzheimer's disease, mean age 53 years.
Statistical Information
P-Value
p = .046, p = .0181, p = .031, p = .023
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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