Spindle Cell Carcinoma with Bone-like Materials in the Gingiva
Author Information
Author(s): Katase Naoki, Tamamura Ryo, Gunduz Mehmet, Murakami Jun, Asaumi Jun-Ichi, Tsukamoto Goichi, Sasaki Akira, Nagatsuka Hitoshi
Primary Institution: Okayama University
Conclusion
This case report presents a unique instance of spindle cell carcinoma with calcified bone-like materials in the gingiva, which is a rare finding in the literature.
Supporting Evidence
- The tumor showed biphasic appearance with both spindle shape and epithelial cells.
- Histological findings included calcified, bone-like materials observed between cancer cells.
- Immunohistochemistry revealed positive reactions for cytokeratins and vimentin in cancer cells.
Takeaway
A 71-year-old man had a rare type of cancer in his gums that formed bone-like materials. This is unusual and hasn't been commonly reported before.
Methodology
The case involved histological examination, MRI imaging, and immunohistochemical analysis to identify the characteristics of the tumor.
Limitations
The detailed mechanism of metaplasia and its effects on clinical features and prognosis are not well established.
Participant Demographics
71-year-old Japanese male.
Digital Object Identifier (DOI)
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