Molecular Identification of Dibothriocephalus nihonkaiense Infection Using Nanopore Sequencing: A Case Report and Literature Review
2024

Identifying a Fish Tapeworm Infection Using Nanopore Sequencing

Sample size: 1 publication 10 minutes Evidence: low

Author Information

Author(s): Tsang Hin-Fung, Leung Stanley W.M., Hung Tin-Nok, Law Icy, Lam Ka-Wai, Chan Loiston, Wong Sze-Chuen Cesar

Primary Institution: Department of Clinical Laboratory and Pathology, Hong Kong Adventist Hospital, Hong Kong SAR, China

Hypothesis

Can Nanopore sequencing accurately identify Dibothriocephalus nihonkaiense infections?

Conclusion

Nanopore sequencing was successfully used to identify a case of Dibothriocephalus nihonkaiense infection in a patient with gastrointestinal symptoms.

Supporting Evidence

  • A curvilinear opacity was seen in the patient's abdomen via X-ray.
  • An 80 cm long strobila of the tapeworm was found in the patient's feces.
  • Nanopore sequencing provided accurate species identification of the parasite.

Takeaway

A woman had a fish tapeworm infection, and doctors used a special DNA test to find out what kind of tapeworm it was.

Methodology

The case was diagnosed using Nanopore sequencing to identify the parasite from fecal samples.

Limitations

The study is based on a single case report, limiting generalizability.

Participant Demographics

A 40-year-old woman from Hong Kong.

Digital Object Identifier (DOI)

10.3390/diagnostics14242871

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