Correlates of Trabecular and Cortical Volumetric Bone Mineral Density of the Radius and Tibia in Older Men: The Osteoporotic Fractures in Men Study
2010

Factors Affecting Bone Density in Older Men

Sample size: 1172 publication Evidence: moderate

Author Information

Author(s): Kamil E Barbour, Joseph M Zmuda, Elsa S Strotmeyer, Mara J Horwitz, Robert Boudreau, Rhobert W Evans, Kristine E Ensrud, Moira A Petit, Christopher L Gordon, Jane A Cauley

Primary Institution: University of Pittsburgh

Hypothesis

What demographic, lifestyle, and medical factors influence volumetric bone mineral density in older men?

Conclusion

The study found that various factors, including age, weight, and education, influence bone mineral density in older men.

Supporting Evidence

  • Age was not correlated with radial trabecular vBMD.
  • Higher body weight was related to greater trabecular vBMD but lower cortical vBMD.
  • Education level was positively associated with trabecular vBMD.
  • History of nontrauma fractures was associated with lower vBMD.
  • Diabetes with TZD use was linked to higher trabecular vBMD.

Takeaway

This study looked at older men to see what affects their bone strength. It found that things like how much you weigh and how much education you have can make a difference.

Methodology

The study used peripheral quantitative computed tomography (pQCT) to measure bone mineral density in older men and analyzed various demographic and lifestyle factors.

Potential Biases

Potential recall bias from self-reported data and a small sample of African American participants may affect the findings.

Limitations

The study's cross-sectional design limits the ability to establish causality, and self-reported data may introduce recall bias.

Participant Demographics

Participants were men aged 69 to 97 years, predominantly white (97.9%), with 61.9% having more than a high school education.

Statistical Information

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/jbmr.6

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