PubSort

Pubsort is a free search engine for publications that pre-summarizes each paper’s key findings, hypothesis, conclusion, and supporting evidence.

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Recent Publications

Impact of Nonsense-Mediated mRNA Decay on Yeast Gene Expression

University of Wisconsin, Madison, Wisconsin, United States of America 2006 n=607 publication 10 minutes Evidence: high

Guan Qiaoning, Zheng Wei, Tang Shijie, Liu Xiaosong, Zinkel Robert A, Tsui Kam-Wah, Yandell Brian S, Culbertson Michael R

Title

Impact of Nonsense-Mediated mRNA Decay on Yeast Gene Expression

Hypothesis

How does nonsense-mediated mRNA decay (NMD) affect the global expression profile of budding yeast?

Conclusion

The study found that NMD significantly influences the expression levels of many mRNAs in yeast, with about 45% of NMD-targeted RNAs being direct targets with altered decay rates.

Detection of Mycobacteria Using Quantum Dots

Agricultural University of Athens 2011 n=7 publication Evidence: moderate

Liandris Emmanouil, Gazouli Maria, Andreadou Margarita, Sechi Leonardo A., Rosu Valentina, Ikonomopoulos John

Title

Detection of Mycobacteria Using Quantum Dots

Hypothesis

Can quantum dots be used to effectively detect mycobacterial surface antigens?

Conclusion

The study demonstrates that a novel assay using quantum dots can specifically detect mycobacterial pathogens with high sensitivity.

Intensivist Supervision Reduces Bloodstream Infections from Central Venous Catheters

University of Toledo College of Medicine 2008 n=85 publication Evidence: moderate

Thomas J Papadimos, Sandra J Hensley, Joan M Duggan, James P Hofmann, Sadik A Khuder, Marilyn J Borst, John J Fath

Title

Intensivist Supervision Reduces Bloodstream Infections from Central Venous Catheters

Hypothesis

Does intensivist supervision during central venous catheter placement reduce the incidence of catheter-related bloodstream infections?

Conclusion

Intensivist supervision during central venous catheter placements significantly decreases the rate of catheter-related bloodstream infections.

Imaging-Based Molecular Interaction Between Src and Lamin A/C in Laminopathic Cells

Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy 2024 n=2 publication Evidence: moderate

Petrini Stefania, Bagnato Giulia, Piccione Michela, D’Oria Valentina, Apollonio Valentina, Cappa Marco, Castiglioni Claudia, Santorelli Filippo Maria, Rizza Teresa, Carrozzo Rosalba, Bertini Enrico Silvio, Peruzzi Barbara

Title

Imaging-Based Molecular Interaction Between Src and Lamin A/C in Laminopathic Cells

Hypothesis

The study investigates the relationship between Src tyrosine kinase and lamin A/C in skin fibroblasts from laminopathic patients.

Conclusion

The study demonstrates a molecular interaction between Src and lamin A/C in healthy fibroblasts and their aberrant interaction in laminopathic nuclei.

Genetic Variants in Decorin and Lumican and Ovarian Cancer Risk

2011 n=5017 publication 10 minutes Evidence: moderate

Amankwah Ernest K., Wang Qinggang, Schildkraut Joellen M., Tsai Ya-Yu, Ramus Susan J., Fridley Brooke L., Beesley Jonathan, Johnatty Sharon E., Webb Penelope M., Chenevix-Trench Georgia, Dale Laura C., Lambrechts Diether, Amant Frederic, Despierre Evelyn, Vergote Ignace, Gayther Simon A., Gentry-Maharaj Aleksandra, Menon Usha, Chang-Claude Jenny, Wang-Gohrke Shan, Anton-Culver Hoda, Ziogas Argyrios, Dörk Thilo, Dürst Matthias, Antonenkova Natalia, Bogdanova Natalia, Brown Robert, Flanagan James M., Kaye Stanley B., Paul James, Bützow Ralf, Nevanlinna Heli, Campbell Ian, Eccles Diana M., Karlan Beth Y., Gross Jenny, Walsh Christine, Pharoah Paul D. P., Song Honglin, Krüger Kjær Susanne, Høgdall Estrid, Høgdall Claus, Lundvall Lene, Nedergaard Lotte, Kiemeney Lambertus A. L. M., Massuger Leon F. A. G., van Altena Anne M., Vermeulen Sita H. H. M., Le Nhu D., Brooks-Wilson Angela, Cook Linda S., Phelan Catherine M., Cunningham Julie M., Vachon Celine M., Vierkant Robert A., Iversen Edwin S., Berchuck Andrew, Goode Ellen L., Sellers Thomas A., Kelemen Linda E.

Title

Genetic Variants in Decorin and Lumican and Ovarian Cancer Risk

Hypothesis

Inherited variation in DCN and LUM may influence the risk of serous epithelial ovarian cancer.

Conclusion

Variants in DCN and LUM are not directly associated with serous epithelial ovarian cancer, and further confirmation of possible effect modification by non-genetic factors is needed.

Opposite Root Growth Phenotypes in Arabidopsis Mutants

Department of Plant Molecular Biology, University of Lausanne, Lausanne, Switzerland 2006 publication 10 minutes Evidence: high

Sibout Richard, Sukumar Poornima, Hettiarachchi Chamari, Holm Magnus, Muday Gloria K, Hardtke Christian S

Title

Opposite Root Growth Phenotypes in Arabidopsis Mutants

Hypothesis

The opposite root system phenotypes of hy5 single and hy5 hyh double mutants represent the morphological response to a quantitative gradient in the same molecular process, that is gradually increased constitutive auxin signaling.

Conclusion

The study concludes that HY5 and HYH are important negative regulators of auxin signaling amplitude in embryogenesis and seedling development.

Improving Poly(3-hydroxybutyrate) with Polyurethane and Cellulose

National Institute for Research & Development in Chemistry and Petrochemistry—ICECHIM, Bucharest, Romania 2024 publication 10 minutes Evidence: moderate

Frone Adriana Nicoleta, Panaitescu Denis Mihaela, Gabor Augusta Raluca, Nicolae Cristian-Andi, Ghiurea Marius, Bradu Corina

Title

Improving Poly(3-hydroxybutyrate) with Polyurethane and Cellulose

Hypothesis

Can blending poly(3-hydroxybutyrate) with polyurethane and microfibrillated cellulose improve its properties?

Conclusion

The addition of polyurethane and microfibrillated cellulose enhances the thermal stability and processability of poly(3-hydroxybutyrate) while delaying its degradation.

Study of Cytisus scoparius for Stress Relief in Rats

J.S.S. College of Pharmacy, Rocklands, Ootacamund, TN, India 2008 n=30 publication 10 minutes Evidence: moderate

Nirmal Jayabalan, Babu Chidambaram Saravana, Harisudhan Thanukrishnan, Ramanathan Muthiah

Title

Study of Cytisus scoparius for Stress Relief in Rats

Hypothesis

Cytisus scoparius has anxiolytic and antioxidant properties that can alleviate stress in rats.

Conclusion

Cytisus scoparius shows moderate anxiolytic activity and improves antioxidant status in stressed rats.

Correction on Hematopoietic Stem Cells Study

Public Library of Science 2006 publication

Carlos A Ramos, Teresa A Bowman, Nathan C Boles, Akil A Merchant, Yayun Zheng, Irma Parra, Suzanne A. Fuqua, Chad A W Shaw, Margaret A Goodell

Title

Correction on Hematopoietic Stem Cells Study

Conclusion

The correction clarifies the composition of the buffers used in the study of transcriptional profiles of single hematopoietic stem cells.

Meiotic DNA Breaks and Repair in Drosophila Females

Waksman Institute, Rutgers, the State University of New Jersey 2006 publication 10 minutes Evidence: moderate

Mehrotra S, McKim K. S

Title

Meiotic DNA Breaks and Repair in Drosophila Females

Hypothesis

How does the timing of meiotic DNA double-strand break (DSB) formation and repair affect crossover frequency in Drosophila females?

Conclusion

The study found that Drosophila females have a weak mechanism to ensure a crossover occurs in the presence of a low number of DSBs.

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