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Recent Publications

Meeting Report on Cancer Research Advances

1992 publication

K. Sikora, M.E. Lippman, A. Wellstein, F. Kern, S. McLeskey, M. Gottardis, N.R. Lemoine, J.L. Bos, R.H. Medema, B.M.Th. Burgering, A.M.M. de Vries-Smits, G.J. Pronk, K. Alitalo, T.P. Miakel'a, P.J. Koskinen, I. Va'strik, G. Evan, M.G. Borrello, M. Shiraishi, T. Sekiya, A.L. Harris, E. Horak, S. LeJeunel, D. Neal, K. Smith, R. Leek, K. Mellon, C. Wright, J. Mendelsohn, R.A. Weinberg, H.C. Hurst, S. Dalton, R. Treisman, R.M. Evans, A. Kakizuka, S. Kliewer, D. Mangelsdorf, K. Umesonol, J. Wagstaff, R.E.N. van Rijswijk, A.C. van Loenen, R. Lopez, C.J. van Groeningen, J.J. Heimans, H.M. Pinedo, H. Thomas, C. Barton, A. Saini, A. Dalgleish, J. Waxman, K. Sisley, D. Cottam, G. Rennie, A.M. Potter, C.W. Potter, R.C. Rees, D. Eccles, L. Gruber, M. Steel, R. Leonard, R. Kalra, K. Wade, M. Greenall, R. Camplejohn, A.L. Harris, G.K. Raddal, B.S. Bolger, T.G. Cooke, P.D. Stanton, A.B. McLean, R.P. Symonds, A. Purohit, L. Duncan, M.J. Reed, C. Galustian, S. Foulds, J.F. Dye, P.J. Guillou, C.H. Wakefield, P.D. Carey, S. Foulds, J. Monson, P.J. Guillou, T. Hickish, C. Clarke, D. Robertson, D. Cunningham, M.A. Raja, R.T.D. Oliver, J. Ong, C.J. Gallagher, R.J. Gilbertson, A.D.J. Pearson, E.B. Jaros, R.H. Perry, C.M. Barton, S.L. Staddon, C.M. Hughes, P.A. Hall, C. O'Sullivan, G. Kloppel, B. Theis, R.C.G. Russell, J. Neoptolemos, R.C.N. Williamson, N.R. Lemoine

Title

Meeting Report on Cancer Research Advances

Conclusion

Recent advances in molecular genetics have identified new targets for cancer therapy, including growth factors and oncogenes.

At-Risk Phenotype of Neurofibromatosis Type 1 Patients

Université Paris Est (UPEC) 2011 n=220 publication 10 minutes Evidence: high

Sbidian Emilie, Bastuji-Garin Sylvie, Valeyrie-Allanore Laurence, Ferkal Salah, Lefaucheur Jean P, Drouet Alain, Brugière Pierre, Vialette Cédric, Combemale Patrick, Barbarot Sébastien, Wolkenstein Pierre

Title

At-Risk Phenotype of Neurofibromatosis Type 1 Patients

Hypothesis

The association between subcutaneous neurofibromas and internal neurofibromas in patients with neurofibromatosis type 1 is related to peripheral neuropathy.

Conclusion

Subcutaneous neurofibromas are significantly associated with internal neurofibromas and axonal neuropathies in neurofibromatosis type 1 patients.

Calculating Left Ventricular Relaxation Time Constant in Aortic Regurgitation

Henderson Research Center, McMaster University 2008 publication

Xufang Bai

Title

Calculating Left Ventricular Relaxation Time Constant in Aortic Regurgitation

Hypothesis

Can a simple method be developed to calculate the left ventricular relaxation time constant, Tau, in patients with aortic regurgitation using continuous-wave Doppler?

Conclusion

A new method for calculating Tau in aortic regurgitation patients using continuous-wave Doppler has been developed, which simplifies the process significantly.

The Earliest Large Carpenter Bee and Its Pollen

University of Vienna 2024 publication 10 minutes Evidence: high

Geier Christian, Engel Michael S., Bouchal Johannes M., Ulrich Silvia, Grímsson Friðgeir, Wedmann Sonja, Wappler Torsten

Title

The Earliest Large Carpenter Bee and Its Pollen

Hypothesis

What can the pollen found on a fossilized carpenter bee tell us about ancient plant-pollinator interactions?

Conclusion

The study reveals the earliest occurrence of the carpenter bee tribe Xylocopini, along with pollen from two plant families, indicating their association in the Eocene ecosystem.

Improving Access to Accelerated Approval for Rare Disease Treatments

Kakkis EveryLife Foundation For Rare Diseases 2011 publication Evidence: moderate

Miyamoto Brigitta E, Kakkis Emil D

Title

Improving Access to Accelerated Approval for Rare Disease Treatments

Hypothesis

Can improved access to accelerated approval reduce development costs and increase the number of treatments for rare diseases?

Conclusion

Better access to accelerated approval could significantly reduce development costs and increase the number of rare disease drugs developed.

Low HDL Cholesterol, Smoking, and IL-13 R130Q Polymorphism Linked to Heart Attacks in Greek Cypriot Men

The Cyprus Institute of Neurology and Genetics 2008 n=156 publication 10 minutes Evidence: moderate

Xenophontos Stavroulla, Hadjivassiliou Marilena, Karagrigoriou Alexandros, Demetriou Nafsika, Miltiadous George, Marcou Ioannis, Elisaf Moses, Mikhailidis Dimitri P, Cariolou Marios A

Title

Low HDL Cholesterol, Smoking, and IL-13 R130Q Polymorphism Linked to Heart Attacks in Greek Cypriot Men

Hypothesis

What are the risk factors for myocardial infarction in Greek Cypriot males?

Conclusion

Smoking and low HDL cholesterol levels are associated with an increased risk of myocardial infarction in Greek Cypriot men.

The Earliest Large Carpenter Bee and Its Pollen

University of Vienna, Department of Botany and Biodiversity Research 2024 publication 10 minutes Evidence: high

Geier Christian, Engel Michael S., Bouchal Johannes M., Ulrich Silvia, Grímsson Friðgeir, Wedmann Sonja, Wappler Torsten

Title

The Earliest Large Carpenter Bee and Its Pollen

Hypothesis

What can the pollen found on a fossilized carpenter bee tell us about ancient plant-insect interactions?

Conclusion

The study identifies the earliest occurrence of a large carpenter bee and its associated pollen, providing insights into ancient pollination relationships.

Comparative Proteomic Analysis of Saccharopolyspora spinosa Strains

Hunan Provincial Key Laboratory of Microbial Molecular Biology, Hunan Normal University 2011 publication Evidence: moderate

Luo Yushuang, Ding Xuezhi, Xia Liqiu, Huang Fan, Li Wenping, Huang Shaoya, Tang Ying, Sun Yunjun

Title

Comparative Proteomic Analysis of Saccharopolyspora spinosa Strains

Hypothesis

What are the differentially expressed proteins correlated with the increase of spinosad yield in Saccharopolyspora spinosa strains?

Conclusion

The study identifies differentially expressed proteins between two strains of Saccharopolyspora spinosa, providing insights into the molecular mechanisms that enhance spinosad production.

Reducing Calories to Treat Breast Cancer in Rats

German Cancer Research Center 1992 n=240 publication Evidence: moderate

B. Bunk, P. Zhu, K. Kling, M.R. Berger, D. Schmihll

Title

Reducing Calories to Treat Breast Cancer in Rats

Hypothesis

Does a change of dietary fat or calorie intake influence the growth of mammary tumors and their recurrence after treatment?

Conclusion

Reducing calorie intake by 30% significantly inhibited the growth of mammary tumors in rats, regardless of dietary fat levels.

Impact of Exercise on Arterial Stiffness in Older Hypertensives

Lawson Health Research Institute at Parkwood Hospital 2008 n=9 publication Evidence: low

Aizawa Kunihiko, Petrella Robert J.

Title

Impact of Exercise on Arterial Stiffness in Older Hypertensives

Hypothesis

Acute maximal treadmill exercise would not reduce arterial stiffness indices at baseline but would reduce them following the 20 weeks of moderate intensity aerobic exercise training.

Conclusion

In older hypertensives, acute maximal dynamic exercise and 20 weeks of moderate intensity aerobic exercise training had no impact on arterial stiffness.

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