PubSort

Pubsort is a free search engine for publications that pre-summarizes each paper’s key findings, hypothesis, conclusion, and supporting evidence.

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Recent Publications

The Role of Chromatin Remodeler SPLAYED in Plant Stress Signaling

University of California, Davis 2008 n=16 publication 10 minutes Evidence: moderate

Justin W. Walley, Heather C. Rowe, Yanmei Xiao, Wassim E. Chehab, Daniel J. Kliebenstein, Doris Wagner, Katayoon Dehesh

Title

The Role of Chromatin Remodeler SPLAYED in Plant Stress Signaling

Hypothesis

Is chromatin remodeling via SPLAYED necessary for plant defense against specific biotic stresses?

Conclusion

Chromatin remodeling is essential for selective pathogen resistance in plants, particularly against Botrytis cinerea.

Health-Related Conditions and Depression in Elderly Mexican American and Non-Hispanic White Residents

Texas Tech University Health Sciences Center 2011 n=1152 publication 10 minutes Evidence: moderate

David F. Briones, Peter L. Heller, Luis M. Carcoba, Henry W. Weisman, Elizabeth M. Ledger, Michael A. Escamilla

Title

Health-Related Conditions and Depression in Elderly Mexican American and Non-Hispanic White Residents

Hypothesis

The study investigates the association between depressive symptoms and health-related conditions in elderly Mexican American and Non-Hispanic White residents.

Conclusion

Elderly Mexican Americans have a higher prevalence of depressive symptoms compared to Non-Hispanic Whites, but many differences in health-related conditions become nonsignificant when adjusting for educational attainment.

Conservation of Ras-Effector Interaction Rates

EMBL-CRG Systems Biology Unit, Centre de Regulacio Genomica, Barcelona, Spain 2008 n=12 publication 10 minutes Evidence: moderate

Kiel Christina, Aydin Dorothee, Serrano Luis

Title

Conservation of Ras-Effector Interaction Rates

Hypothesis

Are the association rate constants of Ras-effector interactions conserved through evolution?

Conclusion

The study found that while sequence similarity decreases over time, the association rate constants for Ras-effector interactions are evolutionarily conserved.

Fatal Retroperitoneal Bleeding from Sigmoid Cancer

VU University Medical Center 2011 n=1 publication Evidence: low

Cornelis G. Vos, Arjan W. J. Hoksbergen

Title

Fatal Retroperitoneal Bleeding from Sigmoid Cancer

Conclusion

The case highlights the need for high suspicion of retroperitoneal bleeding in patients with a history of cancer and anticoagulant use.

Enhanced Proliferation of Cardiomyocytes from Embryonic Stem Cells

Laboratory of Cardiovascular Science, National Institute on Aging, Baltimore, Maryland, United States of America 2008 publication Evidence: moderate

Yamanaka Satoshi, Zahanich Ihor, Wersto Robert P., Boheler Kenneth R.

Title

Enhanced Proliferation of Cardiomyocytes from Embryonic Stem Cells

Hypothesis

Retinoblastoma protein (Rb) regulates cell cycle progression and maturation in embryonic stem cell-derived cardiomyocytes.

Conclusion

The study establishes a model for cardiac cell cycle progression and demonstrates that Rb actively regulates both cell cycle progression and maturation of cardiomyocytes.

Genetic Study of Bipolar Disorder and Schizophrenia in African Americans

Cold Spring Harbor Laboratory 2025 n=17951 publication Evidence: moderate

Li Runjia, Gagliano Taliun Sarah A., Liao Kevin, Flickinger Matthew, Sobell Janet L., Genovese Giulio, Locke Adam E., Chiu Rebeca Rothwell, LeFaive Jonathon, Wang Jiongming, Martins Taylor, Chapman Sinéad, Neumann Anna, Handsaker Robert E., Arnett Donna K., Barnes Kathleen C., Boerwinkle Eric, Braff David, Cade Brian E., Fornage Myriam, Gibbs Richard A., Hoth Karin F., Hou Lifang, Kooperberg Charles, Loos Ruth J.F., Metcalf Ginger A., Montgomery Courtney G., Morrison Alanna C., Qin Zhaohui S., Redline Susan, Reiner Alexander P., Rich Stephen S., Rotter Jerome I., Taylor Kent D., Viaud-Martinez Karine A., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Genomic Psychiatry Cohort investigators, Bigdeli Tim B., Gabriel Stacey, Zollner Sebastian, Smith Albert V., Abecasis Goncalo, McCarroll Steve, Pato Michele T., Pato Carlos N., Boehnke Michael, Knowles James, Kang Hyun Min, Ophoff Roel A., Ernst Jason, Scott Laura J.

Title

Genetic Study of Bipolar Disorder and Schizophrenia in African Americans

Hypothesis

The study investigates the association of genetic variants with bipolar disorder and schizophrenia in African American individuals.

Conclusion

The study found suggestive evidence linking certain genetic variants to bipolar disorder and highlights the importance of further research in African American populations.

Impaired Sympathoadrenal Axis Function and Insulin Secretion in Prediabetic Obese Rats

Federal University of Juiz de Fora 2011 n=40 publication 10 minutes Evidence: moderate

Andreazzi Ana Eliza, Grassiolli Sabrina, Marangon Paula Beatriz, Martins Adriana Gallego, de Oliveira Júlio Cézar, Torrezan Rosana, Gravena Clarice, Garcia Raúl Marcel González, de Freitas Mathias Paulo Cezar

Title

Impaired Sympathoadrenal Axis Function and Insulin Secretion in Prediabetic Obese Rats

Hypothesis

The study investigates the role of sympathoadrenal axis activity in obesity onset and its effect on insulin secretion in prediabetic obese rats.

Conclusion

Low sympathoadrenal activity contributes to impaired glycaemic control in prediabetic obese rats.

Structure of Reovirus σ1 in Complex with Its Receptor JAM-A

Interfaculty Institute for Biochemistry, University of Tuebingen, Tuebingen, Germany 2008 publication 10 minutes Evidence: high

Eva Kirchner, Kristen M. Guglielmi, Holger M. Strauss, Terence S. Dermody, Thilo Stehle

Title

Structure of Reovirus σ1 in Complex with Its Receptor JAM-A

Hypothesis

How does the reovirus attachment protein σ1 interact with the receptor junctional adhesion molecule-A (JAM-A)?

Conclusion

The study reveals that reovirus σ1 binds to JAM-A with a much higher affinity than JAM-A binds to itself, indicating a mechanism for viral attachment.

Genetic Study of Bipolar Disorder and Schizophrenia in African Americans

Cold Spring Harbor Laboratory 2024 n=17963 publication Evidence: moderate

Li Runjia, Gagliano Taliun Sarah A., Liao Kevin, Flickinger Matthew, Sobell Janet L., Genovese Giulio, Locke Adam E., Chiu Rebeca Rothwell, LeFaive Jonathon, Martins Taylor, Chapman Sinéad, Neumann Anna, Handsaker Robert E., Arnett Donna K., Barnes Kathleen C., Boerwinkle Eric, Braff David, Cade Brian E., Fornage Myriam, Gibbs Richard A., Hoth Karin F., Hou Lifang, Kooperberg Charles, Loos Ruth J.F., Metcalf Ginger A., Montgomery Courtney G., Morrison Alanna C., Qin Zhaohui S., Redline Susan, Reiner Alexander P., Rich Stephen S., Rotter Jerome I., Taylor Kent D., Viaud-Martinez Karine A., NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Genomic Psychiatry Cohort investigators, Bigdeli Tim B., Gabriel Stacey, Zollner Sebastian, Smith Albert V., Abecasis Goncalo, McCarroll Steve, Pato Michele T., Pato Carlos N., Boehnke Michael, Knowles James, Kang Hyun Min, Ophoff Roel A., Ernst Jason, Scott Laura J.

Title

Genetic Study of Bipolar Disorder and Schizophrenia in African Americans

Hypothesis

The study investigates the association of genetic variants with bipolar disorder and schizophrenia in African American individuals.

Conclusion

The study found suggestive evidence of genetic associations with bipolar disorder and highlights the importance of further research in African American populations.

Role of Toll-Like Receptors and Decoy Receptors in Systemic Lupus Erythematosus

Università degli Studi di Palermo 2012 publication

Giuliana Guggino, Anna Rita Giardina, Francesco Ciccia, Giovanni Triolo, Francesco Dieli, Guido Sireci

Title

Role of Toll-Like Receptors and Decoy Receptors in Systemic Lupus Erythematosus

Hypothesis

Are Toll-Like Receptors and Decoy Receptors involved in the immunopathogenesis of Systemic Lupus Erythematosus and lupus-like syndromes?

Conclusion

The study highlights the involvement of Toll-like receptors and decoy receptors in the pathogenesis of systemic lupus erythematosus and lupus-like syndromes.

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